Motif ID: FOX{C1,C2}.p2

Z-value: 0.503


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXC1chr6_+_15565430.495.5e-02Click!
FOXC2chr16_+_851583570.341.9e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_158008763 1.083 NM_004288
CYTIP
cytohesin 1 interacting protein
chr6_-_155818728 1.023 NM_015718
NOX3
NADPH oxidase 3
chr2_+_189547323 0.960 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_189547358 0.877 COL3A1
collagen, type III, alpha 1
chr2_+_73973640 0.787 ACTG2
actin, gamma 2, smooth muscle, enteric
chr20_-_60435983 0.776 NM_080833
C20orf151
chromosome 20 open reading frame 151
chr2_-_207291364 0.750 NM_001093730
DYTN
dystrotelin
chr2_+_189547377 0.748 COL3A1
collagen, type III, alpha 1
chr2_+_73973600 0.669 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr14_+_28306633 0.571 FOXG1
forkhead box G1
chr10_-_13316333 0.539 NM_145314
UCMA
upper zone of growth plate and cartilage matrix associated
chr9_-_74735669 0.539 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr4_+_71054492 0.512 NM_214711
C4orf40
chromosome 4 open reading frame 40
chr7_-_98643024 0.491 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr20_-_43609409 0.488 NM_001198986
NM_020398
SPINLW1-WFDC6
SPINLW1
SPINLW1-WFDC6 readthrough
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
chr11_-_67163600 0.454 NM_005995
TBX10
T-box 10
chr11_+_56224436 0.429 NM_001005213
NM_001013358
OR9G1
OR9G9
olfactory receptor, family 9, subfamily G, member 1
olfactory receptor, family 9, subfamily G, member 9
chr17_+_7563763 0.419 NM_020877
DNAH2
dynein, axonemal, heavy chain 2
chr3_-_115826481 0.405 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr20_+_9146036 0.405 NM_182797
PLCB4
phospholipase C, beta 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.77 1.72e-09 GO:0007608 sensory perception of smell
3.37 5.33e-08 GO:0007606 sensory perception of chemical stimulus
2.98 8.56e-03 GO:0016337 cell-cell adhesion
2.49 4.38e-06 GO:0007600 sensory perception
2.39 2.24e-02 GO:0009967 positive regulation of signal transduction
2.35 2.31e-02 GO:0023056 positive regulation of signaling
1.95 3.09e-04 GO:0050877 neurological system process
1.86 1.47e-04 GO:0003008 system process
1.39 6.53e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.93 8.89e-05 GO:0031012 extracellular matrix
2.85 1.53e-03 GO:0005578 proteinaceous extracellular matrix
1.97 5.94e-04 GO:0044421 extracellular region part
1.82 1.34e-06 GO:0005576 extracellular region
1.76 8.06e-03 GO:0005887 integral to plasma membrane
1.73 1.33e-02 GO:0031226 intrinsic to plasma membrane
1.68 1.03e-11 GO:0071944 cell periphery
1.67 2.67e-11 GO:0005886 plasma membrane
1.59 1.73e-03 GO:0044459 plasma membrane part
1.42 1.35e-06 GO:0031224 intrinsic to membrane
1.41 4.60e-06 GO:0016021 integral to membrane
1.37 3.34e-06 GO:0044425 membrane part
1.30 1.13e-05 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
16.78 1.84e-02 GO:0016175 superoxide-generating NADPH oxidase activity
6.61 2.56e-02 GO:0003823 antigen binding
4.05 1.80e-11 GO:0004984 olfactory receptor activity
2.74 1.64e-09 GO:0004930 G-protein coupled receptor activity
2.54 2.75e-12 GO:0004888 transmembrane receptor activity
2.31 8.25e-13 GO:0004872 receptor activity
2.11 9.83e-03 GO:0005509 calcium ion binding
2.10 8.62e-12 GO:0004871 signal transducer activity
2.10 8.62e-12 GO:0060089 molecular transducer activity